Antibiotic resistance mitigation: the development of alternative general strategies

J Mater Chem B. 2020 Aug 5;8(30):6317-6321. doi: 10.1039/d0tb01241f.

Abstract

Antibiotic resistance has become one of the major, deadly threats to public health worldwide. This paper highlights several recent works, which may initiate the development of comprehensive approaches to mitigate antibiotic resistance. The new strategies demonstrate efficiency and efficacy, with very little probability of inducing drug resistance, paving the way for further breakthroughs in drug discovery for infection control.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Cell Membrane / drug effects
  • Colistin / pharmacology
  • Drug Resistance, Microbial
  • Drug Therapy, Combination
  • Global Health
  • Humans
  • Infection Control
  • Organometallic Compounds / pharmacology
  • Photosensitizing Agents / chemistry
  • Photothermal Therapy
  • Reactive Oxygen Species / metabolism

Substances

  • Anti-Bacterial Agents
  • Organometallic Compounds
  • Photosensitizing Agents
  • Reactive Oxygen Species
  • bismuth tripotassium dicitrate
  • Colistin