Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing

J M Lee; S L Sing; W Y Yeong

doi:10.18063/ijb.v6i1.245

Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing

Int J Bioprint. 2020 Jan 22;6(1):245. doi: 10.18063/ijb.v6i1.245. eCollection 2020.

Authors

J M Lee¹, S L Sing¹, W Y Yeong¹

Affiliation

¹ Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.

Abstract

Multimaterials deposition, a distinct advantage in bioprinting, overcomes material's limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integrity of three-dimensional bioprinted construct. A combination of rapid cross-linking hydrogel has been chosen for the build/support setup. The bioprinted construct was further chemically cross-linked to ensure a stable construct after print. This paper also proposes a file segmentation and preparation technique to be used in bioprinting for printing freeform structures.

Keywords: Additive manufacturing; Bioprinting; Computer-aided design; Hydrogel; Rapid prototyping; Support structure generation; Three-dimensional bioprinting; Three-dimensional printing.