Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

Allergy. 2021 Jan;76(1):359-363. doi: 10.1111/all.14477. Epub 2020 Jul 21.

Authors

Affiliations

¹ Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
² Department of Otolaryngology, National Center for Child Health and Development, Tokyo, Japan.
³ Department of Pediatrics, Kochi Medical School, Kochi University, Kochi, Japan.

PMID: 32593215
DOI: 10.1111/all.14477

No abstract available

Keywords: PFAPA syndrome; endotype; innate immune response; phenotype; tonsil.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
Gene Expression Profiling
Humans
Lymphadenitis* / diagnosis
Lymphadenitis* / genetics
Palatine Tonsil
Pharyngitis* / diagnosis
Pharyngitis* / genetics
Stomatitis, Aphthous* / diagnosis
Stomatitis, Aphthous* / genetics