Do You See What I See? A Case of Alice in Wonderland Syndrome With EEG Correlate

Arya Shah; Setty M Magaña; Paul E Youssef

doi:10.1177/2329048X20932714

Do You See What I See? A Case of Alice in Wonderland Syndrome With EEG Correlate

Child Neurol Open. 2020 Jun 12:7:2329048X20932714. doi: 10.1177/2329048X20932714. eCollection 2020 Jan-Dec.

Authors

Arya Shah¹, Setty M Magaña², Paul E Youssef²

Affiliations

¹ Brigham and Women's Hospital, Boston, MA, USA.
² Division of Child and Adolescent Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, USA.

Abstract

Alice in Wonderland syndrome is a disorienting perceptual disorder characterized by discrete episodes of bizarre visual illusions and spatial distortions which has been associated with numerous neurologic and psychiatric conditions. Little is known regarding the electrophysiologic correlates of the visual symptoms described in this syndrome. The authors report the unique case of an 8-year-old boy presenting with visual distortions consistent with Alice in Wonderland syndrome, and an electroencephalogram demonstrating bilateral temporo-occipital slowing which correlated with symptoms of micropsia, teleopsia, and dysmorphopsia. Identification of this clinical syndrome and its electroclinical features are important for establishing a proper diagnosis and subsequent reassurance or appropriate treatment directed toward the underlying etiology.

Keywords: Alice in Wonderland syndrome; EEG; epilepsy; pediatric migraine.