Integrating Pharmacogenetic Decision Support into a Clinical Information System

Stud Health Technol Inform. 2020 Jun 16:270:618-622. doi: 10.3233/SHTI200234.

Abstract

Pharmacogenetic testing can prevent adverse drug events but has rarely found its way into clinical routine. One reason is the lack of tools for smooth and automatable integration of pharmacogenetic knowledge into existing processes. Especially, electronic medical records (EMR) represent a suitable environment for such tools. We developed a modular service-oriented prototype of a pharmacogenetic decision support system within an EMR system of the Bern University Hospital. Here, we present the component architecture of our system and discuss issues required for generalizing our results.

Keywords: HL7 FHIR; Pharmacogenomics; adverse drug events; decision support; expert system; pharmacogenetics.

MeSH terms

  • Decision Support Systems, Clinical
  • Electronic Health Records
  • Pharmacogenetics
  • Pharmacogenomic Testing*
  • Software