From Fad to Fact: Evaluating the Impact of Emerging Diets on the Prevention of Cardiovascular Disease

Am J Med. 2020 Oct;133(10):1126-1134. doi: 10.1016/j.amjmed.2020.05.017. Epub 2020 Jun 19.

Abstract

Cardiovascular disease remains one of the most prevalent and preventable chronic conditions worldwide. Diet modification is the foundation of cardiovascular disease prevention. Several dietary approaches have emerged to promote better cardiovascular health. The rapid dissemination of anecdotal and observational data through the internet and social media has caused confusion amongst providers and patients. The aim of this comprehensive review is to present objective insights into 2 of today's most popular fad diets: ketogenic diet and intermittent fasting. We will evaluate the performance of these diets based on their impact on cardiovascular risk factors.

Keywords: Cardiovascular disease prevention; Intermittent fasting; Ketogenic diet; Metabolic syndrome.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Atrial Fibrillation
  • Blood Glucose / metabolism
  • Blood Pressure
  • Cardiovascular Diseases / prevention & control*
  • Cholesterol, HDL / metabolism
  • Cholesterol, LDL / metabolism
  • Diabetes Mellitus, Type 2 / diet therapy
  • Diabetes Mellitus, Type 2 / prevention & control
  • Diet Fads
  • Diet, Ketogenic / methods*
  • Dyslipidemias / metabolism*
  • Fasting*
  • Humans
  • Insulin Resistance
  • Lipid Metabolism
  • Obesity / metabolism
  • Risk Reduction Behavior
  • Triglycerides / metabolism
  • Weight Loss

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Triglycerides