Data highlighting phenotypic diversity of urine-associated Escherichia coli isolates

Data Brief. 2020 Jun 3:31:105811. doi: 10.1016/j.dib.2020.105811. eCollection 2020 Aug.

Abstract

This article provides a reusable dataset describing detailed phenotypic and associated clinical parameters in n=303 clinical isolates of urinary Escherichia coli collected at Vanderbilt University Medical Center. De-identified clinical data collected with each isolate are detailed here and correlated to biofilm abundance and metabolomics data. Biofilm-abundance data were collected for each isolate under different in vitro conditions along with datasets quantifying biofilm abundance of each isolate under different conditions. Metabolomics data were collected from a subset of bacterial strains isolated from uncomplicated cases of cystitis or cases with no apparent symptoms accompanying colonization. For more insight, please see "Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities" [1].

Keywords: Asymptomatic bacteriuria; Biofilm; Cystitis; Metabolomics; Urinary tract infection; Uropathogenic Escherichia coli.