Contributions of the National Institute of Parasitic Diseases to the control of visceral leishmaniasis in China

Zheng-Bin Zhou; Jun-Yun Wang; Chun-Hua Gao; Shuai Han; Yuan-Yuan Li; Yi Zhang; Xiao-Nong Zhou

doi:10.1016/bs.apar.2020.04.003

Contributions of the National Institute of Parasitic Diseases to the control of visceral leishmaniasis in China

Adv Parasitol. 2020:110:185-216. doi: 10.1016/bs.apar.2020.04.003. Epub 2020 Jun 10.

Authors

Zheng-Bin Zhou¹, Jun-Yun Wang¹, Chun-Hua Gao¹, Shuai Han¹, Yuan-Yuan Li¹, Yi Zhang¹, Xiao-Nong Zhou²

Affiliations

¹ National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China; Chinese Center for Tropical Diseases Research, Shanghai, People's Republic of China; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, People's Republic of China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, People's Republic of China; School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
² National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China; Chinese Center for Tropical Diseases Research, Shanghai, People's Republic of China; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, People's Republic of China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, People's Republic of China; School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. Electronic address: zhouxn1@chinacdc.cn.

PMID: 32563325
DOI: 10.1016/bs.apar.2020.04.003

Abstract

Visceral leishmaniasis (VL) caused by Leishmania spp. is an important vector-borne disease prevalent in China. VL was rampant in the vast area of China north of the Yangtze River before the founding of the People's Republic of China in 1949. As a result of strenuous interventions, the disease was basically eliminated in most of the former epidemic areas in 1958-60. At present, only sporadic cases occur in the western regions of China. In the process, National Institute of Parasitic Diseases at China CDC and the Chinese Center for Tropical Diseases Research (NIPD-CTDR) have achieved great impact in controlling the diseases as well as in research on Leishmania spp. This review summarized the contribution of experts from NIPD-CTDR to the control and elimination of VL in various aspects, such as understanding the epidemiological features of VL, confirmation of VL vectors and their distribution, development of control tools including diagnostics and insecticides, monitoring and evaluation supported by information management, technical supports to the control programmes, as well as analysis of the challenges faced. At the same time, it puts forward constructive suggestions for the ultimate interruption of VL transmission in China.

Keywords: China; Diagnostics; Geographical distribution; Kala-azar; Monitoring; Phlebotomus; Sandfly; Vector control; Visceral leishmaniasis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Academies and Institutes*
Animals
Biomedical Research*
China / epidemiology
Government Programs*
Humans
Leishmaniasis, Visceral / epidemiology*
National Health Programs*