Current treatment approaches for COVID-19 and the clinical value of transfusion-related technologies

Transfus Apher Sci. 2020 Oct;59(5):102839. doi: 10.1016/j.transci.2020.102839. Epub 2020 Jun 3.

Abstract

COVID-19 is caused by SARS-CoV-2 which is a new enveloped virus that belongs to the Beta coronavirus genus. As a major health crisis, SARS-CoV-2 has infected over a million people around the world. There is currently no specific treatment available for patients with COVID-19 infection. Numerous potential therapies, including supportive intervention, immunomodulatory agents, antiviral therapy, and convalescent plasma transfusion, have been used in clinical practice. Herein, we summarize the current potential therapeutic approaches for diseases related to COVID-19 infection and discusses the clinical value of blood transfusion-related technologies used in COVID-19 treatment.

Keywords: COVID-19; Convalescent plasma; Mesenchymal stem cell; Plasmapheresis.

Publication types

  • Review

MeSH terms

  • Blood Component Transfusion*
  • COVID-19 / immunology
  • COVID-19 / therapy*
  • COVID-19 Serotherapy
  • Free Radicals / metabolism
  • Humans
  • Immunization, Passive
  • SARS-CoV-2 / physiology

Substances

  • Free Radicals