A novel deep feature transfer-based OSA detection method using sleep sound signals

Physiol Meas. 2020 Aug 11;41(7):075009. doi: 10.1088/1361-6579/ab9e7b.

Abstract

Objective: Polysomnography is typically used to evaluate the severity of obstructive sleep apnea (OSA) but the inconvenience of application and high cost considerably affect the diagnostics. In this study, sleep sound signals are used to detect OSA in patients.

Approach: A deep feature transfer-based OSA detection approach is proposed. First, a deep convolutional neural network is trained on large-scale labeled audio data sets to distinguish respiration sounds from environmental noise. Second, the trained model is transferred to recognize respiration sounds in sleep sound signals. Third, the deep features of the detected respiration sounds are used to train a logistic regression classifier to identify OSA patients from potential patients. Polysomnography-based diagnosis is used as a reference.

Main results: A self-collected data set of 132 potential OSA patients is applied in OSA detection experiments. The OSA detection performances are tested on four models for different apnea-hypopnea index thresholds and sexes resulting in accuracies of 80.17%, 80.21%, 81.63% and 77.22%. The corresponding areas under the receiver operating characteristic curves are 0.82, 0.80, 0.81 and 0.79. In addition, the proposed method presented a significant performance improvement compared with the state-of-the-art methods.

Significance: Big data, deep learning and transfer learning can be successfully applied to improve diagnostic accuracy in OSA detection. The performance of the proposed approach is superior to that of traditional audio analysis technology. The proposed method significantly reduces difficulties in OSA detection and diagnosis, such that potential OSA patients can perform initial inspections by themselves at home.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Neural Networks, Computer
  • Polysomnography
  • Respiratory Sounds*
  • Signal Processing, Computer-Assisted*
  • Sleep
  • Sleep Apnea, Obstructive* / diagnosis