Natural history of intracranial meningiomas

Chad A Glenn; Hurtis J Tullos; Michael E Sughrue

doi:10.1016/B978-0-12-804280-9.00014-7

Natural history of intracranial meningiomas

Handb Clin Neurol. 2020:169:205-227. doi: 10.1016/B978-0-12-804280-9.00014-7.

Authors

Chad A Glenn¹, Hurtis J Tullos¹, Michael E Sughrue²

Affiliations

¹ Department of Neurological Surgery, University of Oklahoma, Oklahoma City, OK, United States.
² Department of Neurosurgery, Prince of Wales Hospital, Randwick, NSW, Australia. Electronic address: sughruevs@gmail.com.

PMID: 32553291
DOI: 10.1016/B978-0-12-804280-9.00014-7

Abstract

We know that the extent of resection is the greatest predictor of long-term survival. However, the potential tradeoff for gross total resection in difficult locations is diminished quality of life. Benign subtotally resected or small incidentally discovered meningiomas may be followed clinically especially in the elderly. In addition, radiosurgery plays a role in the treatment of meningiomas as a primary treatment modality, or as a salvage therapy. Decisions regarding management should be made with an understanding of the natural history and rate of growth. In this chapter we review the known meningioma epidemiology as well as the growth patterns of meningiomas based upon location.

Keywords: Meningioma; Natural history; Observation.

Publication types

Review

MeSH terms

Humans
Meningeal Neoplasms / epidemiology*
Meningeal Neoplasms / surgery
Meningioma / epidemiology*
Meningioma / surgery*
Microsurgery / methods
Neoplasm Recurrence, Local / epidemiology
Neoplasm Recurrence, Local / surgery*
Quality of Life