[Intranuclear cytoplasmic autophagosomes cause specific nucleolysis and cell death of liver cancer cells and liver cells]

Zhonghua Gan Zang Bing Za Zhi. 2020 May 20;28(5):449-451. doi: 10.3760/cma.j.cn501113-20190529-00193.
[Article in Chinese]

Abstract

The structure and performance of nuclear cytoplasmic autophagosomes was explored. Seventeen cases of hepatocellular carcinoma and liver cells with other diseases from liver tissues were selected. The nuclear cytoplasm were isolated and degraded by the nuclear membrane. Damaged cytoplasm had damaged its own membrane and the surrounding nuclear tissues other than the nuclear membrane, leading to specific nucleolysis and cell death of liver cancer cells and liver cells.

探索核内胞质性自噬体的结构和性能,从肝组织内选择17例肝细胞癌和患有其他疾病的肝细胞。核内胞质会被核膜隔离和降解,被破坏的胞质会损伤自身胞膜和除核膜以外的周围核组织,导致特殊性核溶解和细胞死亡。.

Keywords: Carcinoma, hepatocellular; Cell death; Hepatocytes; Specific nucleolysis.

MeSH terms

  • Autophagosomes*
  • Carcinoma, Hepatocellular*
  • Cell Death*
  • Cytoplasm
  • Humans
  • Liver
  • Liver Neoplasms*