Molecular mimicry may explain multi-organ damage in COVID-19

Francesca Angileri; Sébastien Legare; Antonella Marino Gammazza; Everly Conway de Macario; Alberto Jl Macario; Francesco Cappello

doi:10.1016/j.autrev.2020.102591

Molecular mimicry may explain multi-organ damage in COVID-19

Autoimmun Rev. 2020 Aug;19(8):102591. doi: 10.1016/j.autrev.2020.102591. Epub 2020 Jun 11.

Authors

Francesca Angileri¹, Sébastien Legare², Antonella Marino Gammazza³, Everly Conway de Macario⁴, Alberto Jl Macario⁵, Francesco Cappello⁶

Affiliations

¹ Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Cancer Research Center of Lyon, Lyon, France.
² Département d'Informatique de l'ÉNS, ÉNS, CNRS, Université PSL, Paris, France; Centre de recherche Inria de Paris, Paris, France.
³ University of Palermo, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Palermo, Italy.
⁴ Department of Microbiology and Immunology, School of Medicine, University of Maryland at Baltimore-Institute of Marine and Environmental Technology (IMET), Baltimore, MD 21202, USA.
⁵ Department of Microbiology and Immunology, School of Medicine, University of Maryland at Baltimore-Institute of Marine and Environmental Technology (IMET), Baltimore, MD 21202, USA; Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy.
⁶ University of Palermo, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Palermo, Italy; Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy. Electronic address: francesco.cappello@unipa.it.

No abstract available

Keywords: Anosmia; Kawasaki vasculitis; Leukopenia; Molecular mimicry; OR7D4; PARP9; SLC12A6; Severe acute respiratory syndrome coronavirus 2; Vascular damage.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Autoimmune Diseases / immunology
Autoimmune Diseases / virology*
Betacoronavirus / chemistry
Betacoronavirus / immunology*
COVID-19
Coronavirus Infections / immunology*
Coronavirus Infections / virology*
Cross Reactions
Epitopes / chemistry
Epitopes / immunology
Humans
Models, Immunological*
Molecular Mimicry / immunology*
Pandemics
Pneumonia, Viral / immunology*
Pneumonia, Viral / virology*
SARS-CoV-2

Substances

Epitopes