[Oral complications following allogeneic hematopoietic cell transplantation: Recommendations of the Francophone Society of Bone Marrow transplantation and cellular Therapy (SFGM-TC)]

Bull Cancer. 2020 Dec;107(12S):S122-S129. doi: 10.1016/j.bulcan.2020.03.017. Epub 2020 Jun 10.
[Article in French]

Abstract

Stomatological complications of allogeneic hematopoietic stem cell transplantation (HSCT) are frequent and very uncomfortable for patients. The primary complication is the graft versus host disease reaction. Other side effects of the procedure include infections, taste disorders and carcinogenic risks. Various local treatments are used but remain imperfect. Within the framework of the 10th workshop of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held in Lille in September 2019, diagnostic approaches and treatments of tongue and oral complications following allogeneic HSCT were reviewed according to the analysis of published studies.

Keywords: Allogeneic stem cell transplantation; Allogreffe de cellules souches hématopoïétiques; Complications stomatologiques; Oral GVHD; Réaction du greffon contre l’hôte buccale; Tongue and oral complications.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Acute Disease
  • Candidiasis, Oral / diagnosis
  • Candidiasis, Oral / etiology
  • Candidiasis, Oral / therapy
  • Carcinoma, Squamous Cell / etiology
  • Chronic Disease
  • Dental Caries / etiology
  • Dental Caries / prevention & control
  • Gout / etiology
  • Graft vs Host Disease / complications
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Mouth Diseases / diagnosis
  • Mouth Diseases / etiology*
  • Mouth Diseases / therapy
  • Mouth Neoplasms / etiology
  • Periodontal Diseases / etiology
  • Societies, Medical
  • Tongue Diseases / diagnosis
  • Tongue Diseases / etiology
  • Tongue Diseases / therapy
  • Transplantation Conditioning / adverse effects
  • Transplantation, Homologous / adverse effects