Efficacy of Velopharyngeal Surgery for Positional Obstructive Sleep Apnea Hypopnea Syndrome

Ear Nose Throat J. 2021 Dec;100(10_suppl):999S-1003S. doi: 10.1177/0145561320931956. Epub 2020 Jun 11.

Abstract

Background: Positional obstructive sleep apnea hypopnea syndrome (P-OSAHS) is a distinct OSAHS type. Whether velopharyngeal surgery is efficacious for patients with P-OSAHS remains unclear.

Aim/objective: To investigate the efficacy and factors influencing velopharyngeal surgery for treatment of patients with P-OSAHS, defined as the apnea hypopnea index (AHI) in different body postures (supine AHI ≥2*nonsupine AHI).

Materials and methods: A total of 44 patients with P-OSAHS who underwent velopharyngeal surgery were retrospectively studied. The clinical data of these patients, including polysomnography (PSG), physical examination, and surgical information, were collected for analysis. All patients underwent a PSG about 6 months after surgery to determine the treatment outcomes.

Results: The overall AHI of the 44 patients decreased from 40.2 ± 18.7 events/h to 18.5 ± 17.5 events/h after surgery (P < .001). There were 29 responders (65.9%) according to the classical definition of surgical success. The percentage of sleep time with oxygen saturation below 90% (CT90) was the only predictive parameter for surgical success (P = .014, odds ratio value = 0.894). There was no significant difference between the change in supine AHI (-55.9 ± 35.2%) and the change in nonsupine AHI (-43.4 ± 74.1%; P = .167), and these 2 parameters were significantly correlated (r = 0.616, P < .001). Among the 38 patients with residual OSAHS (residual AHI ≥5), 28 had persistent P-OSAHS, and the percentage was as high as 82.4%.

Conclusions and significance: Patients with P-OSAHS with a lower CT90 value are more likely to benefit from velopharyngeal surgery. Positional therapy could be indicated for most of the patients who are not cured by such surgery.

Keywords: apnea hypopnea index; polysomnography; positional obstructive sleep apnea hypopnea syndrome; velopharyngeal surgery.

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Otorhinolaryngologic Surgical Procedures / methods*
  • Oxygen Saturation
  • Patient Positioning
  • Pharyngeal Muscles / surgery*
  • Polysomnography
  • Postoperative Period
  • Posture*
  • Retrospective Studies
  • Severity of Illness Index
  • Sleep
  • Sleep Apnea, Obstructive / physiopathology*
  • Sleep Apnea, Obstructive / surgery*
  • Treatment Outcome
  • Young Adult