Soil-sebum partition coefficients for high molecular weight polycyclic aromatic hydrocarbons (HMW-PAH)

Darren J Beriro; Mark Cave; Alex Kim; Jonathan Craggs; Joanna Wragg; Russell Thomas; Christopher Taylor; C Paul Nathanail; Christopher Vane

doi:10.1016/j.jhazmat.2020.122633

Soil-sebum partition coefficients for high molecular weight polycyclic aromatic hydrocarbons (HMW-PAH)

J Hazard Mater. 2020 Nov 5:398:122633. doi: 10.1016/j.jhazmat.2020.122633. Epub 2020 May 13.

Authors

Darren J Beriro¹, Mark Cave², Alex Kim², Jonathan Craggs³, Joanna Wragg², Russell Thomas⁴, Christopher Taylor⁵, C Paul Nathanail⁶, Christopher Vane²

Affiliations

¹ British Geological Survey, Nicker Hill, Keyworth, Nottinghamshire, NG12 5GG, UK. Electronic address: darrenb@bgs.ac.uk.
² British Geological Survey, Nicker Hill, Keyworth, Nottinghamshire, NG12 5GG, UK.
³ University of Nottingham, School of Geography, University Park, Nottingham, UK.
⁴ WSP, WSP House, 70 Chancery Lane, London, WC2A 1AF, UK.
⁵ National Grid Property Holdings Ltd. National Grid House, Warwick Technology Park, Gallows Hill, Warwick, CV34 6DA, UK.
⁶ British Geological Survey, Nicker Hill, Keyworth, Nottinghamshire, NG12 5GG, UK; Land Quality Management, Sir Colin Campbell Building, University of Nottingham Innovation Park, Nottingham NG7 2TU, UK.

PMID: 32512434
DOI: 10.1016/j.jhazmat.2020.122633

Abstract

In vitro high molecular weight polycyclic aromatic hydrocarbons (HMW-PAH) soil-sebum partition coefficients (K_SS) were measured for twelve soils collected from former UK gasworks. Concentrations of ∑16 USEPA PAH in the soils ranged from 51 to 1440 mg/kg. Time series extractions (0.5, 1, 2, 4, 8 and 24 h) at skin temperature (32 °C) of HMW-PAH from sebum to soil for two samples were conducted to determine the maximum release time-step. The maximum HMW-PAH release time-step was determined as 4 h, which was subsequently used as the extraction time for the remaining samples. The 4 h extraction for all samples showed HMW-PAH K_SS ranging from 0.06 to 1.4 (median = 0.59; mean = 0.59; standard deviation = 0.27; median absolute deviation = 0.29). Evaluation of K_SS data for the 4 h extractions showed that soil type and selected HMW-PAH properties (literature based molecular weight and octanol-carbon partition coefficients) affect the amount of HMW-PAH released from soil into sebum.

Keywords: Bioaccessibility; Bioavailability; Dermal; Percutaneous; Skin.