Postherpetic neuralgia and recalcitrant cystic lesions following herpes zoster: A case report and review of treatment options

Dermatol Ther. 2020 Jul;33(4):e13793. doi: 10.1111/dth.13793. Epub 2020 Jul 12.

Abstract

Acute herpes zoster lesions in most cases are self-limited except in older and immunocompromised patients, wherein the pain can cause significant suffering. Postherpetic neuralgia is a painful situation for patients that can compromise the quality of life. Here, we report a 30-year-old healthy young man who developed treatment-resistant postherpetic neuralgia after herpes zoster (fourth/fifth thoracic segment) without any underlying immunocompromised state. He also developed some cystic lesions, which were removed by aspiration and surgery. The skin lesions improved 2 weeks after the surgery and postherpetic neuralgia was completely cured after 5 months, however cystic lesions recurred multiple times and were excised completely during each visit. Postherpetic neuralgia has a significant impact on the health-care cost borne by the society and affected individual, hence, it is essential to select appropriate treatment to manage the pain of postherpetic neuralgia.

Keywords: cystic lesions; herpes zoster; postherpetic neuralgia; treatment-resistant.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Herpes Zoster* / complications
  • Herpes Zoster* / diagnosis
  • Herpes Zoster* / drug therapy
  • Humans
  • Male
  • Neuralgia, Postherpetic* / diagnosis
  • Neuralgia, Postherpetic* / drug therapy
  • Neuralgia, Postherpetic* / etiology
  • Quality of Life
  • Recurrence