[Classification and Diagnosis of Primary Progressive Aphasia]

Brain Nerve. 2020 Jun;72(6):611-621. doi: 10.11477/mf.1416201571.
[Article in Japanese]

Abstract

I have introduced primary progressive aphasia (PPA) with regard to frontotemporal lobar degeneration (FTLD) and evaluated the following elementary language symptoms for its diagnosis: agrammatism in speech production, apraxia of speech, phonemic paraphasia, naming impairment, impairment of single-word comprehension, and repetition. Furthermore, I have described the clinical symptoms, causative lesions, and pathological findings of three PPA variants -nonfluent/agrammatic, semantic, and logopenic PPA- according to the criteria proposed by Gorno-Tempni et al. (2011).

MeSH terms

  • Aphasia* / etiology
  • Aphasia, Primary Progressive* / complications
  • Aphasia, Primary Progressive* / diagnosis
  • Frontotemporal Dementia* / complications
  • Frontotemporal Dementia* / diagnosis
  • Frontotemporal Lobar Degeneration* / complications
  • Frontotemporal Lobar Degeneration* / diagnosis
  • Humans
  • Speech