Silicone Oil-Associated Extensive Intraocular Ossification: A case report

Eur J Ophthalmol. 2021 Sep;31(5):NP53-NP56. doi: 10.1177/1120672120925785. Epub 2020 Jun 5.

Abstract

Background: Intraocular ossification is an uncommon calcium deposition process associated with trauma, chronic inflammation, tumor, and long-standing retinal detachment. This is the first reported extensive intraocular bone formation associated with silicone oil.

Case presentation: A 30-year-old Han Chinese man came to us with complaint of red, painful blind right eye. He had a history of ocular trauma, retinal detachment, and two failed retinal reattachment surgeries with silicone oil left in the eye. On examination, conjunctiva congestion, band keratopathy, silicone oil emulsification, and limbus neovascularization were found. B-scan ultrasound and computed tomography scanning demonstrated retinal detachment and calcification of the eyeball wall. Histopathological analysis indicated ossification overlying the choroid. Evisceration was finally operated to relieve the pain.

Conclusion: The retention of silicone oil in the eye probably accelerates the ossification. Timely silicone oil removal and evisceration should be recommended if necessary for phthisis bulbi.

Keywords: Intraocular ossification; calcium deposition; silicone oil.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eye Injuries*
  • Humans
  • Male
  • Osteogenesis
  • Retinal Detachment* / diagnosis
  • Retinal Detachment* / etiology
  • Retinal Detachment* / surgery
  • Silicone Oils / adverse effects
  • Vitrectomy

Substances

  • Silicone Oils