Abstract
There is no consensus treatment for patients with autoimmune hepatitis (AIH) - primary biliary cholangitis (PBC) overlap syndrome who are not responding to conventional therapy. We present a case of a 43-yr-old woman with AIH-PBC overlap syndrome treated with obeticholic acid (OCA). The patient showed a reduction in liver enzymes and no fibrosis progression during 15 months of follow up.
MeSH terms
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Adult
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Chenodeoxycholic Acid / analogs & derivatives
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Chenodeoxycholic Acid / therapeutic use
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Female
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Hepatitis, Autoimmune* / complications
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Hepatitis, Autoimmune* / drug therapy
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Humans
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Liver Cirrhosis, Biliary* / complications
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Liver Cirrhosis, Biliary* / drug therapy
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Ursodeoxycholic Acid / therapeutic use
Substances
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obeticholic acid
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Chenodeoxycholic Acid
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Ursodeoxycholic Acid