Drug therapy problems identified among older adults placed in a nursing home: the Croatian experience

J Int Med Res. 2020 Jun;48(6):300060520928791. doi: 10.1177/0300060520928791.

Abstract

Objective: The aim of this study was to determine the frequency and type of drug therapy problems (DTPs) in older institutionalized adults.

Method: We conducted a cross-sectional observational study from February to June 2016 at a 150-bed public nursing home in Croatia, where comprehensive medication management (CMM) services were provided. A rational decision-making process, referred to as the Pharmacotherapy Workup method, was used to classify DTPs.

Results: Data were prospectively collected from 73 residents, among which 71% were age 75 years or older. The median number of prescribed medications per patient was 7 (2-16) and polypharmacy (> 4) was recorded for 54 (74.0%) patients. A total 313 DTPs were identified, with an average of 4.3 ± 2 DTPs per patient. The most frequent DTP was needing additional drug therapy (n = 118; 37.7%), followed by adverse drug reaction (n = 55; 17.6%). Lactulose (14.4%), tramadol (6.7%), and potassium (6.4%) were the medications most frequently related to DTPs.

Conclusion: The high prevalence of DTPs identified among older institutionalized adults strongly suggests the need to incorporate new pharmacist-led CMM services within existing institutional care facilities, to improve the care provided to nursing home residents.

Keywords: Nursing home; comprehensive medication management services; drug therapy problems; older adults; pharmaceutical care; polymedication.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Croatia / epidemiology
  • Cross-Sectional Studies
  • Drug-Related Side Effects and Adverse Reactions / epidemiology*
  • Drug-Related Side Effects and Adverse Reactions / prevention & control
  • Female
  • Health Services Needs and Demand
  • Humans
  • Male
  • Medication Therapy Management / organization & administration*
  • Nursing Homes / organization & administration
  • Nursing Homes / statistics & numerical data*
  • Pharmacists / organization & administration
  • Polypharmacy
  • Prevalence
  • Prospective Studies
  • Quality Improvement