Immune Response to the Enteric Parasite Entamoeba histolytica

Physiology (Bethesda). 2020 Jul 1;35(4):244-260. doi: 10.1152/physiol.00038.2019.

Abstract

Entamoeba histolytica is a protozoan parasite responsible for amoebiasis, a disease with a high prevalence in developing countries. Establishing an amoebic infection involves interplay between pathogenic factors for invasion and tissue damage, and immune responses for protecting the host. Here, we review the pathogenicity of E. histolytica and summarize the latest knowledge on immune response and immune evasion mechanisms during amoebiasis.

Keywords: Entamoeba histolytica; NETosis; amoebiasis; immunity; inflammation; neutrophil.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Entamoeba histolytica / immunology*
  • Entamoebiasis / immunology*
  • Entamoebiasis / parasitology
  • Entamoebiasis / pathology
  • Humans
  • Immunity
  • Intestine, Small / immunology*
  • Intestine, Small / metabolism
  • Intestine, Small / parasitology
  • Neutrophils / immunology*
  • Neutrophils / pathology