Functional clustering and coupling of ion channels in cellular mechanosensing is independent on lipid raft integrity in plasma membrane

Biochim Biophys Acta Mol Cell Res. 2020 Oct;1867(10):118764. doi: 10.1016/j.bbamcr.2020.118764. Epub 2020 May 30.

Authors

Vladislav I Chubinskiy-Nadezhdin¹, Valeria Y Vasileva², Yuri A Negulyaev², Elena A Morachevskaya²

Affiliations

¹ Institute of Cytology RAS, St. Petersburg, Russia. Electronic address: vchubinskiy@gmail.com.
² Institute of Cytology RAS, St. Petersburg, Russia.

PMID: 32479769
DOI: 10.1016/j.bbamcr.2020.118764

No abstract available

Keywords: Lipid rafts; Local calcium signaling; Mechanotransduction; Membrane cholesterol; Patch-clamp; SAC-KCa channel cluster.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line
Cluster Analysis
Ion Channel Gating
Ion Channels / metabolism*
Mechanotransduction, Cellular*
Membrane Microdomains / metabolism*
Membrane Potentials
Mice

Substances

Ion Channels