G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 2018

Takako Utsumi; Rury M Wahyuni; Zayyin Dinana; Emily Gunawan; Arga S D Putra; Teguh Mubawadi; Soetjipto; Maria I Lusida; Ikuo Shoji

doi:10.1016/j.jiph.2020.05.002

G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 2018

J Infect Public Health. 2020 Oct;13(10):1592-1594. doi: 10.1016/j.jiph.2020.05.002. Epub 2020 May 29.

Authors

Takako Utsumi¹, Rury M Wahyuni², Zayyin Dinana², Emily Gunawan³, Arga S D Putra², Teguh Mubawadi⁴, Soetjipto², Maria I Lusida², Ikuo Shoji⁵

Affiliations

¹ Indonesia-Japan Collaborative Research Center for Emerging and Re-emerging Infectious Diseases, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia; Center for Infectious Diseases, Kobe University Graduate School of Medicine, Hyogo, Japan. Electronic address: tutsumi@people.kobe-u.ac.jp.
² Indonesia-Japan Collaborative Research Center for Emerging and Re-emerging Infectious Diseases, Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia.
³ Institute of Tropical Disease, Airlangga University, Surabaya, Indonesia.
⁴ Surveillance team from Regional Center for Environmental Health and Disease Control of Surabaya, Indonesia.
⁵ Center for Infectious Diseases, Kobe University Graduate School of Medicine, Hyogo, Japan.

PMID: 32475806
DOI: 10.1016/j.jiph.2020.05.002

Abstract

Rotavirus is a major cause of acute gastroenteritis (AGE) in children worldwide. However, rotavirus outbreak has rarely been reported in Indonesia. This study aims to identify the causative agent for AGE outbreak among children in Belu, East Nusa Tenggara, Indonesia in 2018. All the samples were negative for bacteria (Salmonella, V. cholera) and Norovirus. Ten out of 11 stool samples were rotavirus-positive by immunochromatography testing. Reverse-transcription polymerase chain reaction (RT-PCR) and phylogenetic analyses revealed that rotavirus G2P[4] was the possible causative agent for the AGE outbreak, although sample size was limited. These findings suggest that the AGE outbreak was caused by rotavirus G2P[4], highlighting the importance of rotavirus surveillance.

Keywords: Epidemiology; Gastroenteritis; Outbreak; Rotavirus; Surveillance.

MeSH terms

Child
Disease Outbreaks
Feces
Genotype
Humans
Indonesia / epidemiology
Infant
Phylogeny
Reverse Transcriptase Polymerase Chain Reaction
Rotavirus Infections* / epidemiology
Rotavirus* / genetics