Urinary Frequency as a Possibly Overlooked Symptom in COVID-19 Patients: Does SARS-CoV-2 Cause Viral Cystitis?

Eur Urol. 2020 Oct;78(4):624-628. doi: 10.1016/j.eururo.2020.05.013. Epub 2020 May 19.

Abstract

The current coronavirus disease 2019 (COVID-19) pandemic is a challenge for physicians in triaging patients in emergency rooms. We found a potentially dangerous overlap of classical urinary symptoms and the as yet not fully described symptoms of COVID-19. After a patient was primarily triaged as a urosepsis case and then subsequently diagnosed with COVID-19, we focused on an increase in urinary frequency as a symptom of COVID-19 and identified this in seven males out of 57 patients currently being treated in our COVID-19 wards. In the absence of any other causes, urinary frequency may be secondary to viral cystitis due to underlying COVID-19 disease. We propose consideration of urinary frequency as an anamnestic tool in patients with infective symptoms to increase awareness among urologists during the current COVID-19 pandemic to prevent fatal implications of misinterpreting urological symptoms.

Keywords: COVID-19; Triage; Urinary frequency; Urinary infection; Viral cystitis.

MeSH terms

  • Aged
  • Betacoronavirus / pathogenicity*
  • COVID-19
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Coronavirus Infections / complications
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / virology*
  • Cystitis / diagnosis
  • Cystitis / physiopathology
  • Cystitis / virology*
  • Host-Pathogen Interactions
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / virology*
  • Prospective Studies
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2
  • Time Factors
  • Urinary Incontinence, Urge / diagnosis
  • Urinary Incontinence, Urge / physiopathology
  • Urinary Incontinence, Urge / virology*
  • Urinary Tract Infections / diagnosis
  • Urinary Tract Infections / physiopathology
  • Urinary Tract Infections / virology*
  • Urination*
  • Urodynamics*