Novel dose escalation to predict treatment with hydroxyurea (NDEPTH): A randomized controlled trial of a dose-prediction equation to determine maximum tolerated dose of hydroxyurea in pediatric sickle cell disease

Am J Hematol. 2020 Sep;95(9):E242-E244. doi: 10.1002/ajh.25883. Epub 2020 Jul 4.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / drug therapy*
  • Anemia, Sickle Cell / mortality
  • Child
  • Female
  • Humans
  • Hydroxyurea / administration & dosage*
  • Hydroxyurea / adverse effects
  • Male
  • Maximum Tolerated Dose*

Substances

  • Hydroxyurea