Sero-evaluation of Immune Responses to Vibrio cholerae in a Postelimination Setting

Open Forum Infect Dis. 2020 Apr 21;7(5):ofaa136. doi: 10.1093/ofid/ofaa136. eCollection 2020 May.

Abstract

Cholera remains a significant public health problem worldwide. In settings of declining incidence, serosurveillance may be used to augment clinical surveillance. We utilized dried blood spot sampling and cholera-specific antibody testing to examine the serologic profiles of vaccinated and unvaccinated children in southern Vietnam, where cholera was recently eliminated.

Keywords: Vietnam; antibody; cholera; dried blood spots; serosurveillance.