What is the optimal duration of intravenous antibiotics following single-stage revision total hip arthroplasty for prosthetic joint infection? A systematic review

Hip Int. 2021 May;31(3):286-294. doi: 10.1177/1120700020922850. Epub 2020 May 27.

Abstract

Prosthetic joint infection (PJI) is 1 of the most challenging potential complications following total joint arthroplasty. Several surgical treatment strategies have been proposed for management of this diagnosis. The single-stage approach has been gaining popularity in contemporary literature. 1 fundamental aspect in the management of hip PJI is the administration of antibiotics, usually intravenously immediately after surgery, followed by a period of oral antibiotics. The optimal duration of the period of antibiotic therapy is undecided. The aim of this paper is to examine the trend in intravenous antibiotic use over the last 18 years and examine the influence this has had on the results of single-stage revision over that time period.

Keywords: Antibiotics; duration; hip; intravenous antibiotics; prosthetic joint infection.

Publication types

  • Systematic Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious*
  • Arthroplasty, Replacement, Hip* / adverse effects
  • Humans
  • Prosthesis-Related Infections* / diagnosis
  • Prosthesis-Related Infections* / drug therapy
  • Prosthesis-Related Infections* / surgery
  • Reoperation

Substances

  • Anti-Bacterial Agents