IkCa and SKCa might participate in preeclampsia through regulating placental angiogenesis

Ik_Ca and SK_Ca might participate in preeclampsia through regulating placental angiogenesis

Pregnancy Hypertens. 2020 Jul:21:90-95. doi: 10.1016/j.preghy.2020.04.013. Epub 2020 May 15.

¹ Department of Gynecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
² Department of Gynecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: tjdengdongrui@126.com.

No abstract available

Apoptosis
Cell Movement
Cell Proliferation
Cells, Cultured
Female
Fibroblast Growth Factors / metabolism
Human Umbilical Vein Endothelial Cells / drug effects
Human Umbilical Vein Endothelial Cells / metabolism*
Human Umbilical Vein Endothelial Cells / pathology
Humans
Insulin-Like Growth Factor I / metabolism
Intermediate-Conductance Calcium-Activated Potassium Channels / antagonists & inhibitors
Intermediate-Conductance Calcium-Activated Potassium Channels / metabolism*
Neovascularization, Pathologic*
Placenta / blood supply*
Potassium Channel Blockers / pharmacology
Pre-Eclampsia / drug therapy
Pre-Eclampsia / metabolism*
Pre-Eclampsia / pathology
Pregnancy
Signal Transduction
Small-Conductance Calcium-Activated Potassium Channels / antagonists & inhibitors
Small-Conductance Calcium-Activated Potassium Channels / metabolism*
Vascular Endothelial Growth Factor A / metabolism