Crosslinkable polymeric contrast agent for high-resolution X-ray imaging of the vascular system

Chem Commun (Camb). 2020 Jun 4;56(44):5885-5888. doi: 10.1039/c9cc09883f. Epub 2020 May 26.

Abstract

A contrast agent for X-ray micro computed tomography (μCT), called XlinCA, that combines reliable perfusion and permanent retention and contrast properties, was developed for ex vivo imaging. The new imaging agent XlinCA features high molecular weight, low viscosity and a high iodine content.

MeSH terms

  • Adrenal Glands / blood supply
  • Adrenal Glands / diagnostic imaging
  • Animals
  • Blood Vessels / diagnostic imaging*
  • Brain / blood supply
  • Brain / diagnostic imaging
  • Contrast Media / pharmacology*
  • Intestines / blood supply
  • Intestines / diagnostic imaging
  • Kidney / blood supply
  • Kidney / diagnostic imaging
  • Liver / blood supply
  • Liver / diagnostic imaging
  • Mice
  • Polymers / pharmacology*
  • X-Ray Microtomography / methods*

Substances

  • Contrast Media
  • Polymers