Status of human brucellosis in district Malakand, Khyber Pakhtunkhwa, Pakistan

J Infect Public Health. 2021 Mar;14(3):423-427. doi: 10.1016/j.jiph.2019.12.013. Epub 2020 May 18.

Abstract

Background: Brucellosis is a zoonotic disease caused by the bacteria, Brucella genus. Human is always an accidental host, infected from domesticated or wild animals.

Methods: This study was conducted from September 2017 to April 2018. A total of 304 samples were collected in eight months duration from female of high-risk population connected with domesticated animals to investigate the sero-prevalence of Brucellosis using ELISA (Igm) in District Malakand, Khyber Pakhtunkhwa, Pakistan.

Results: The high age wise prevalence was recorded as 32.25% in female with age group 21-30 by ELISA (P<0.05). The prevalent rate was significantly high (P<0.05) in Tehsil Batkhela (32.8%) than Dargai (22.75%). It was also recorded in the present study that the prevalence was higher from January to April. It was found 20.58%, 17.64%, 14.70%, 20.58%, 17.6%, 38.23%, 45.71% and 44.11% from September to April respectively.

Conclusion: The present study concluded that the prevalence of brucellosis is significantly high among the age group 20-40 and from January to April 2018. Further studies will be required to show the prevalence of the Brucellosis all over the country.

Keywords: Brucella; ELISA; Sero-prevalence.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Brucella / isolation & purification*
  • Brucellosis / blood*
  • Brucellosis / epidemiology*
  • Brucellosis / ethnology
  • Brucellosis / transmission
  • Cattle
  • Child
  • Cross-Sectional Studies
  • Dairy Products / microbiology*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Livestock*
  • Male
  • Middle Aged
  • Milk / microbiology*
  • Pakistan / epidemiology
  • Prevalence
  • Rural Population
  • Seroepidemiologic Studies
  • Young Adult
  • Zoonoses / epidemiology