COVID-19 and inflammatory bowel disease: questions arising from patient care and follow-up during the initial phase of the pandemic (February-April 2020)

Gastroenterol Hepatol. 2020 Aug-Sep;43(7):408-413. doi: 10.1016/j.gastrohep.2020.05.003. Epub 2020 May 15.
[Article in English, Spanish]

Abstract

COVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was described in China in late 2019. There are currently more than three million diagnosed cases, constituting a pandemic which has caused a worldwide crisis. The devastating effects of this infection are due to its highly contagious nature and although mild forms predominate, in absolute values, the rates for severe forms and mortality are very high. The information on the characteristics of the infection in inflammatory bowel disease is of special interest, as these patients have higher attendance at health centres, which may increase their risk of infection. Furthermore, the treatments used to control the inflammatory activity may modify the disease course of COVID-19. The Spanish Working Group on Crohn's Disease and Ulcerative Colitis and the Spanish Nurses Working Group on Inflammatory Bowel Disease have prepared this document as a practical response to some common questions about the treatment of these patients.

Keywords: COVID-19; Colitis ulcerosa; Crohn's disease; Enfermedad de Crohn; Enfermedad inflamatoria intestinal; Inflammatory bowel disease; SARS-CoV-2; Ulcerative colitis.

Publication types

  • Practice Guideline

MeSH terms

  • Anxiety / etiology
  • Betacoronavirus*
  • Biological Products / adverse effects
  • Biological Products / therapeutic use
  • COVID-19
  • COVID-19 Drug Treatment
  • COVID-19 Testing
  • Clinical Laboratory Techniques
  • Comorbidity
  • Contraindications, Drug
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / prevention & control
  • Coronavirus Infections / transmission
  • Diarrhea / etiology
  • Disease Susceptibility
  • Drug Interactions
  • Endoscopy, Gastrointestinal / adverse effects
  • Family Characteristics
  • Fear
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Inflammatory Bowel Diseases / complications
  • Inflammatory Bowel Diseases / drug therapy
  • Inflammatory Bowel Diseases / epidemiology*
  • Occupational Diseases / prevention & control
  • Pandemics* / prevention & control
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / prevention & control
  • Pneumonia, Viral / transmission
  • Quarantine
  • Risk
  • SARS-CoV-2
  • Spain / epidemiology
  • Vitamin B 12 / administration & dosage
  • Vitamin B 12 Deficiency / drug therapy
  • Vitamin B 12 Deficiency / etiology
  • Workplace

Substances

  • Biological Products
  • Immunosuppressive Agents
  • Vitamin B 12