SnapShot: COVID-19

Blake Oberfeld; Aditya Achanta; Kendall Carpenter; Pamela Chen; Nicole M Gilette; Pinky Langat; Jordan Taylor Said; Abigail E Schiff; Allen S Zhou; Amy K Barczak; Shiv Pillai

doi:10.1016/j.cell.2020.04.013

SnapShot: COVID-19

Cell. 2020 May 14;181(4):954-954.e1. doi: 10.1016/j.cell.2020.04.013. Epub 2020 Apr 30.

Affiliations

¹ Harvard Medical School, Boston, MA 02115, USA.
² Harvard Medical School, Boston, MA 02115, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address: abigail_schiff@hms.harvard.edu.
³ Harvard Medical School, Boston, MA 02115, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.

Abstract

Coronavirus disease 2019 (COVID-19) is a novel respiratory illness caused by SARS-CoV-2. Viral entry is mediated through viral spike protein and host ACE2 enzyme interaction. Most cases are mild; severe disease often involves cytokine storm and organ failure. Therapeutics including antivirals, immunomodulators, and vaccines are in development. To view this SnapShot, open or download the PDF.

MeSH terms

Animals
Betacoronavirus / classification
Betacoronavirus / genetics
Betacoronavirus / physiology*
COVID-19
COVID-19 Drug Treatment
COVID-19 Testing
COVID-19 Vaccines
Clinical Laboratory Techniques / methods
Coronavirus Infections / diagnosis
Coronavirus Infections / drug therapy
Coronavirus Infections / immunology
Coronavirus Infections / pathology*
Coronavirus Infections / prevention & control
Coronavirus Infections / therapy
Coronavirus Infections / transmission
Humans
Pandemics
Pneumonia, Viral / immunology
Pneumonia, Viral / pathology*
Pneumonia, Viral / therapy
Pneumonia, Viral / transmission
SARS-CoV-2
Viral Vaccines / immunology

Substances

COVID-19 Vaccines
Viral Vaccines

Grants and funding

T32 GM007753/GM/NIGMS NIH HHS/United States