Human pharmaceutical and pesticide residues in Israeli dairy milk in association with dietary risk assessment

Food Addit Contam Part B Surveill. 2020 Dec;13(4):233-243. doi: 10.1080/19393210.2020.1764114. Epub 2020 May 14.

Abstract

Throughout the world, more than six billion people consume milk and milk products yearly. The safety and quality of dairy milk are regularly monitored in most countries worldwide. The Israeli monitoring program of chemical residues in milk has not changed in the last decades, focusing only on major veterinary drugs and few selected environmental contaminants such as heavy metals and persistent organic pollutants. Consequently, a knowledge gap exists regarding the potential occurrence of other chemicals such as human pharmaceuticals and non-monitored pesticides in milk. In this survey, 51 commercial bovine and goat milk samples were analysed by LC-MS/MS and pharmaceutical and pesticide residues are reported in the range of 0.1-93 µg/L. Israeli milk samples revealed at least one and up to five chemical residues simultaneously. The pesticides found in milk were below the European maximum residue limit values. The risk assessment performed, indicated negligible risk.

Keywords: Dairy milk; human pharmaceuticals; pesticide; risk assessment.

MeSH terms

  • Animals
  • Cattle
  • Chromatography, High Pressure Liquid
  • Diet*
  • Drug Residues / analysis*
  • Environmental Pollutants / analysis
  • Food Contamination / analysis*
  • Goats
  • Humans
  • Israel
  • Maximum Allowable Concentration
  • Milk / chemistry*
  • Pesticide Residues / analysis*
  • Reproducibility of Results
  • Risk Assessment
  • Tandem Mass Spectrometry
  • Veterinary Drugs / analysis

Substances

  • Environmental Pollutants
  • Pesticide Residues
  • Veterinary Drugs