Modeling retinal detachment associated with hemorrhage by Monte Carlo simulation

Appl Opt. 2020 Apr 20;59(12):3614-3618. doi: 10.1364/AO.385247.

Abstract

In this work we study fundus reflection in the case of retinal detachment. Vitreous humor builds up beneath the retina through a break in the retina or when there is traction on the retina. Further, we assume that this detachment is associated with hemorrhage in regions both above and below the retina. To investigate hemorrhage, we assume erythrocytes to be spheres of different radii. Then we apply Mie scattering theory to these spheres and calculate the scattering coefficient, the absorption coefficient, and the anisotropy factor. Using these parameters, we apply Monte Carlo simulation to calculate reflection. In order to model fundus reflection under retinal detachment, we define three types of reflection: reflection from the vitreous body, retinal reflection where photons are reflected from the retinal vitreous interface once, and retinal reflection where photons are reflected many times from the retinal vitreous interface.

MeSH terms

  • Computer Simulation*
  • Humans
  • Mathematics
  • Monte Carlo Method
  • Retinal Detachment / pathology*
  • Retinal Hemorrhage / pathology*
  • Vitreous Hemorrhage / pathology*