A Rare Case of Fungal Burn Wound Infection Caused by Fusarium solani in Vietnam

J Investig Med High Impact Case Rep. 2020 Jan-Dec:8:2324709620912122. doi: 10.1177/2324709620912122.

Abstract

A patient with extensive burn injuries was admitted to the National Hospital of Burns in Hanoi, Vietnam, and diagnosed with fungal wound infection by histological examination of skin biopsy samples. Fusarium solani was isolated and identified by analysis of its morphological features and the sequence of the internal transcribed spacer region. The isolation showed in vitro resistant to fluconazole, voriconazole, itraconazole, amphotericin B, and caspofungin. Invasive fusariosis is difficult to treat due to its angioinvasive property and its lacking amenability to treatment with antifungal drugs. This infection is rare and has not been reported so far in Vietnam.

Keywords: Fusarium solani; Vietnam; fungal wound infection; fusariosis.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / pharmacology
  • Burns / complications
  • Fusariosis / drug therapy*
  • Fusariosis / microbiology*
  • Fusarium / isolation & purification*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Treatment Outcome
  • Vietnam
  • Wound Infection / drug therapy*
  • Wound Infection / microbiology*
  • Young Adult

Substances

  • Antifungal Agents

Supplementary concepts

  • Fusarium solani