Primary Central Nervous System Posttransplant Lymphoproliferative Disorder After Kidney Transplant

J Pediatr Hematol Oncol. 2021 May 1;43(4):144-146. doi: 10.1097/MPH.0000000000001818.

Abstract

Primary central nervous system posttransplant lymphoproliferative disorder is a rare complication of solid organ transplantation, with increasing incidence in children given a steady rise in pediatric solid organ transplants. Given similar imaging appearance to many opportunistic infections, a high degree of awareness is required for prompt and early diagnosis. We report a case of primary central nervous system posttransplant lymphoproliferative disorder presenting as a single rim enhancing lesion with central restricted diffusion mimicking an intracranial abscess.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology*
  • Child
  • Epstein-Barr Virus Infections / complications
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / therapy
  • Kidney Transplantation* / adverse effects
  • Lymphoproliferative Disorders / complications
  • Lymphoproliferative Disorders / diagnosis*
  • Lymphoproliferative Disorders / pathology
  • Lymphoproliferative Disorders / therapy
  • Male

Substances

  • Immunosuppressive Agents