Cryptic Splice-Altering Variants in MYBPC3 Are a Prevalent Cause of Hypertrophic Cardiomyopathy

Affiliations

• ¹ Inherited Cardiovascular Disease Unit, St Bartholomew's Hospital, Barts Health NHS Trust (L.R.L., E.Q., P.M.E.).
• ² UCL Centre for Heart Muscle Disease, Institute of Cardiovascular Science, University College London, United Kingdom (L.R.L., J.J., M.F., P.S., P.M.E.).
• ³ European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart (ERN GUARD-HEART; http://guardheart.ern-net.eu/) (L.R.L., P.M.E.).
• ⁴ Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina (P.B., M.C.-F.), Universidade de Lisboa, Portugal.
• ⁵ LASIGE, Faculdade de Ciências (P.B.), Universidade de Lisboa, Portugal.
• ⁶ Institute of Health Sciences, University of A Coruña (M.T.).
• ⁷ Cardiology Department, University Hospital of Burgos (A.M.).
• ⁸ Cardiology Department, Health in Code, A Coruña, Spain (J.P.O., L.M.).