A new chemiluminescence method for the determination of 8-hydroxyguanine based on l-histidine bound nickel nanoparticles

Xi-Luan Yan; Meng-Meng Jiang; Ying Hu; Le Wu; Kun Zhao; Xin-Xin Xue; Xiang-Juan Zheng

doi:10.1039/d0cc01746a

A new chemiluminescence method for the determination of 8-hydroxyguanine based on l-histidine bound nickel nanoparticles

Chem Commun (Camb). 2020 Jun 18;56(48):6535-6538. doi: 10.1039/d0cc01746a. Epub 2020 May 12.

Authors

Xi-Luan Yan¹, Meng-Meng Jiang, Ying Hu, Le Wu, Kun Zhao, Xin-Xin Xue, Xiang-Juan Zheng

Affiliation

¹ College of Resources, Environment and Chemical Engineering, Nanchang University, Nanchang 330031, P. R. China.

PMID: 32395729
DOI: 10.1039/d0cc01746a

Abstract

A new chemiluminescence aptasensor for sensitive and efficient detection of 8-hydroxyguanine based on the synergistic interaction of Ni NPs@l-histidine@aptamer@MBs has been developed, and it has been applied in the real urine samples of cancer patients.

MeSH terms

Aptamers, Nucleotide / chemistry
Guanine / analogs & derivatives*
Guanine / analysis
Guanine / urine
Histidine / chemistry*
Humans
Luminescent Measurements / methods*
Magnetics
Metal Nanoparticles / chemistry*
Neoplasms / diagnosis
Nickel / chemistry*

Substances

Aptamers, Nucleotide
Histidine
8-hydroxyguanine
Guanine
Nickel