Effect of aerobic exercise on cortical thickness in patients with schizophrenia-A dataset

Shun Takahashi; Daniel Keeser; Boris-Stephan Rauchmann; Thomas Schneider-Axmann; Katriona Keller-Varady; Isabel Maurus; Peter Dechent; Thomas Wobrock; Alkomiet Hasan; Andrea Schmitt; Birgit Ertl-Wagner; Berend Malchow; Peter Falkai

doi:10.1016/j.dib.2020.105517

Effect of aerobic exercise on cortical thickness in patients with schizophrenia-A dataset

Data Brief. 2020 Apr 17:30:105517. doi: 10.1016/j.dib.2020.105517. eCollection 2020 Jun.

Authors

Shun Takahashi^{1

2}, Daniel Keeser^{1

3}, Boris-Stephan Rauchmann^{1

3}, Thomas Schneider-Axmann¹, Katriona Keller-Varady¹, Isabel Maurus¹, Peter Dechent⁴, Thomas Wobrock^{5

6}, Alkomiet Hasan¹, Andrea Schmitt^{1

7}, Birgit Ertl-Wagner^{3

8}, Berend Malchow^{1

5}, Peter Falkai¹

Affiliations

¹ Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nussbaumstraße 7, 80336 Munich, Germany.
² Department of Neuropsychiatry, Wakayama Medical University, 811-1 Kimiidera, 6410012 Wakayama, Japan.
³ Department of Radiology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
⁴ Institute for Cognitive Neurology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany.
⁵ Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Von-Siebold-Straße 5, D-37075 Göttingen, Germany.
⁶ Centre of Mental Health, County Hospitals Darmstadt-Dieburg, Krankenhausstraße 7, 64823 Groß-Umstadt, Germany.
⁷ Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, 05403-010 São Paulo, Brazil.
⁸ Department of Medical Imaging, University of Toronto, McCaul Street 263, Toronto M5T1W7, Ontario, Canada.

Abstract

This is a data article from the original publication "Effect of aerobic exercise combined with cognitive remediation on cortical thickness and prediction of social adaptation in patients with schizophrenia" [1]. Twenty-one patients with schizophrenia and 23 healthy controls underwent aerobic exercise. Another 21 patients with schizophrenia played table soccer instead. The 12-week exercise intervention was combined with computer-assisted cognitive remediation training from week 6 to week 12. Clinical assessments were conducted at baseline and after the 12-week intervention. Magnetic resonance imaging (MRI) scans were acquired at baseline then in weeks 6, 12, and 24. The thickness of the entorhinal, parahippocampal, and lateral and medial prefrontal cortices was assessed with FreeSurfer 6.0. Data are publicy available via https://osf.io/sfgxk/.

Keywords: Aerobic exercise; Clinical symptoms; Cortical thickness; FreeSurfer; Magnetic resonance imaging (MRI); Schizophrenia.