Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature

Muhammad Waqas; Maxim Mokin; Jaims Lim; Kunal Vakharia; Michael E Springer; Karen M Meess; Richard W Ducharme; Ciprian N Ionita; Swetadri Vasan Setlur Nagesh; Liza C Gutierrez; Kenneth V Snyder; Jason M Davies; Elad I Levy; Adnan H Siddiqui

doi:10.1093/neuros/nyaa134

Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature

Neurosurgery. 2020 Sep 15;87(4):E445-E453. doi: 10.1093/neuros/nyaa134.

Authors

Muhammad Waqas^{1

2}, Maxim Mokin³, Jaims Lim^{1

2}, Kunal Vakharia^{1

2}, Michael E Springer⁴, Karen M Meess⁴, Richard W Ducharme⁴, Ciprian N Ionita⁵, Swetadri Vasan Setlur Nagesh^{1

5}, Liza C Gutierrez⁵, Kenneth V Snyder^{1

2}, Jason M Davies^{1

2

4

6}, Elad I Levy^{1

2

4

5}, Adnan H Siddiqui^{1

2

4

5

7}

Affiliations

¹ Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.
² Department of Neurosurgery, Gates Vascular Institute at Kaleida Health, Buffalo, New York.
³ Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida.
⁴ Jacobs Institute, Buffalo, New York.
⁵ Canon Stroke and Vascular Research Center, University at Buffalo, Buffalo, New York.
⁶ Department of Bioinformatics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.
⁷ Department of Radiology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Abstract

Background: Three-dimensional (3D) printing has revolutionized training, education, and device testing. Understanding the design and physical properties of 3D-printed models is important.

Objective: To systematically review the design, physical properties, accuracy, and experimental outcomes of 3D-printed vascular models used in neurointervention.

Methods: We conducted a systematic review of the literature between January 1, 2000 and September 30, 2018. Public/Publisher MEDLINE (PubMed), Web of Science, Compendex, Cochrane, and Inspec databases were searched using Medical Subject Heading terms for design and physical attributes of 3D-printed models for neurointervention. Information on design and physical properties like compliance, lubricity, flow system, accuracy, and outcome measures were collected.

Results: A total of 23 articles were included. Nine studies described 3D-printed models for stroke intervention. Tango Plus (Stratasys) was the most common material used to develop these models. Four studies described a population-representative geometry model. All other studies reported patient-specific vascular geometry. Eight studies reported complete reconstruction of the circle of Willis, anterior, and posterior circulation. Four studies reported a model with extracranial vasculature. One prototype study reported compliance and lubricity. Reported circulation systems included manual flushing, programmable pistons, peristaltic, and pulsatile pumps. Outcomes included thrombolysis in cerebral infarction, post-thrombectomy flow restoration, surgical performance, and qualitative feedback.

Conclusion: Variations exist in the material, design, and extent of reconstruction of vasculature of 3D-printed models. There is a need for objective characterization of 3D-printed vascular models. We propose the development of population representative 3D-printed models for skill improvement or device testing.

Keywords: Aneurysm; Arteriovenous malformation; Compliance; Lubricity; Neurointervention; Stroke; Three-dimensional (3D) printed model; Tortuosity.

Publication types

Systematic Review

MeSH terms

Humans
Models, Anatomic*
Neurosurgical Procedures / methods
Neurosurgical Procedures / trends*
Printing, Three-Dimensional / trends*
Prostheses and Implants / trends*
Prosthesis Design / methods
Prosthesis Design / trends*

Abstract

Publication types

MeSH terms

Grants and funding