Genomic profiling of acute myeloid leukaemia associated with ataxia telangiectasia identifies a complex karyotype with wild-type TP53 and mutant KRAS, G3BP1 and IL7R

Pediatr Blood Cancer. 2020 Sep;67(9):e28354. doi: 10.1002/pbc.28354. Epub 2020 May 8.

Mae A Goldgraben¹, Eleanor Fewings¹, Alexey Larionov¹, James Scarth¹, James Redman¹, Nick Telford², Peter D Arkwright^{3

4}, Denise Bonney⁵, Deepti Wilks⁶, Samar Kulkarni⁷, A Malcolm R Taylor⁸, Marc D Tischkowitz¹, Stefan Meyer^{5

9

10

11}

¹ Academic Department of Medical Genetics, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
² Oncology Cytogenetics, The Christie NHS Foundation Trust, Manchester, UK.
³ Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK.
⁴ Department of Paediatric Immunology, Royal Manchester Children's Hospital, Central Manchester Foundation Trust, Manchester, UK.
⁵ Department of Paediatric Hematology and Oncology, Royal Manchester Children's Hospital, Central Manchester Foundation Trust, Manchester, UK.
⁶ Manchester Cancer Research Centre Biobank, The Christie NHS Foundation Trust, Manchester, UK.
⁷ Department of Haematology, The Christie NHS Foundation Trust, Manchester, UK.
⁸ Institute of Cancer & Genomic Sciences, University of Birmingham, Birmingham, UK.
⁹ Young Oncology Unit, The Christie NHS Trust, Manchester, UK.
¹⁰ Stem Cell and Leukemia Proteomics Laboratory, University of Manchester, Manchester, UK.
¹¹ Paediatric and Adolescent Oncology, Division of Molecular and Clinical Cancer Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK.

No abstract available

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