Insights into the effect of cerium oxide nanoparticle on microalgal degradation of sulfonamides

Abstract

Nanoparticles have been commercially used worldwide; however, there is a lack of information of their environmental impacts and ecotoxicity. In this study, the effect of cerium oxide nanoparticle (CeO₂NP) on a green microalga Scenedesmus obliquus, and microalgal biodegradation of four sulfonamides (sulfamethazine, sulfamethoxazole, sulfadiazine, and sulfamethoxazole) was investigated. There is insignificant inhibition of microalgal growth induced by CeO₂NP; however, it substantially influenced the expression of genes involved in key cellular metabolic activities of S. obliquus. For example, genes involved in photosynthetic activity (psbA) and energy production (ATPF0C) were downregulated with exposure to CeO₂NP. The low concentrations of CeO₂NP improved microalgal degradation of sulfonamides. This may be because of the upregulated genes encoding hydrogenase and oxidoreductase. The exploration of this study has provided a new understanding of the environmental impacts of CeO₂NP on microalgae-based biotechnologies for treatment of wastewater containing emerging organic contaminants.

Keywords: Biodegradation; Cerium oxide nanoparticle; Ecotoxicity; Microalgae; Sulfonamide antibiotic.