Acute on chronic liver failure from novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Liver Int. 2020 Jul;40(7):1590-1593. doi: 10.1111/liv.14506. Epub 2020 May 20.

Abstract

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious viral disease that predominantly causes respiratory symptoms. Elevated liver enzymes have been reported during the course of disease and appear to be common. We present a 56-year-old woman with a history of decompensated alcoholic cirrhosis who presented with abdominal pain, fever and diarrhoea and was found to have acute on chronic liver failure secondary to SARS-CoV-2 infection. The patient was treated with empiric antibiotic and supportive care with subsequent improvement.

Keywords: COVID-19; SARS-CoV-2; acute on chronic liver failure.

Publication types

  • Case Reports

MeSH terms

  • Acute-On-Chronic Liver Failure / diagnosis
  • Acute-On-Chronic Liver Failure / therapy
  • Acute-On-Chronic Liver Failure / virology*
  • Anti-Bacterial Agents / therapeutic use
  • Betacoronavirus / pathogenicity*
  • COVID-19
  • Coronavirus Infections / complications
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / therapy
  • Coronavirus Infections / virology*
  • Female
  • Fluid Therapy
  • Host-Pathogen Interactions
  • Humans
  • Liver Cirrhosis, Alcoholic / complications*
  • Liver Cirrhosis, Alcoholic / diagnosis
  • Liver Cirrhosis, Alcoholic / therapy
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / therapy
  • Pneumonia, Viral / virology*
  • SARS-CoV-2
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents