Recurrent Phyllodes Tumour of the Breast Transforming to a Fibrosarcoma

Dua Jabeen; Lubna M Vohra Sr; Tariq Siddiqui; Aziz-Un-Nisa Raza

doi:10.7759/cureus.7457

Recurrent Phyllodes Tumour of the Breast Transforming to a Fibrosarcoma

Cureus. 2020 Mar 29;12(3):e7457. doi: 10.7759/cureus.7457.

Authors

Dua Jabeen¹, Lubna M Vohra Sr², Tariq Siddiqui³, Aziz-Un-Nisa Raza⁴

Affiliations

¹ Medicine, Jinnah Sindh Medical University, Karachi, PAK.
² Breast Surgery, Aga Khan University Hospital, Karachi, PAK.
³ Oncology, Ziauddin University Hospital, Karachi, PAK.
⁴ Pathology, Ziauddin University Hospital, Karachi, PAK.

Abstract

Phyllodes tumours of the breast are characterized by having both an epithelial as well as stromal component and these usually comprise almost 3% of all fibroepithelial tumours. They are exceptional in this aspect to convert into a stromal sarcoma of the breast after multiple recurrences. To the best of our knowledge, there are only three case reports regarding this in the available literature as it is an exceptional change. In this case report, we present a case of recurrent phyllodes transforming into a breast fibrosarcoma in a middle age postmenopausal woman. Histopathological examination and immunohistochemistry of the lesion were performed to confirm the diagnosis of breast fibrosarcoma.

Keywords: breast; fibrosarcoma; phyllodes tumour.

Publication types

Case Reports