Frequent occurrence of CD19-negative relapse after CD19 CAR T and consolidation therapy in 14 TP53-mutated r/r B-ALL children

Leukemia. 2020 Dec;34(12):3382-3387. doi: 10.1038/s41375-020-0831-z. Epub 2020 Apr 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, CD19 / genetics*
  • Child
  • Consolidation Chemotherapy / methods
  • Humans
  • Leukemia, Biphenotypic, Acute / drug therapy*
  • Leukemia, Biphenotypic, Acute / genetics*
  • Mutation / genetics
  • Receptors, Antigen, T-Cell / genetics
  • Receptors, Chimeric Antigen / genetics*
  • Recurrence
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Antigens, CD19
  • Receptors, Antigen, T-Cell
  • Receptors, Chimeric Antigen
  • TP53 protein, human
  • Tumor Suppressor Protein p53