SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis

Khalid M Dousa; Sharad S Malavade; Jennifer Furin; Barbara Gripshover; Marjorie Hatszegi; Leila Hojat; Elie Saade; Robert A Salata

doi:10.1016/j.idcr.2020.e00778

SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis

IDCases. 2020 Apr 27:20:e00778. doi: 10.1016/j.idcr.2020.e00778. eCollection 2020.

Authors

Khalid M Dousa¹, Sharad S Malavade¹, Jennifer Furin¹, Barbara Gripshover¹, Marjorie Hatszegi^{1

2}, Leila Hojat¹, Elie Saade¹, Robert A Salata^{1

2}

Affiliations

¹ Division of Infectious Diseases and HIV Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.
² Roe Green Center for Travel Medicine and Global Health, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Abstract

People exposed to COVID-19 have a risk of developing disease, and health care workers are at risk at a time when they are badly needed during a health care crisis. Hydroxychloroquine and chloroquine have been used as treatment and are being considered as prophylaxis. Our patient developed COVID-19 while on hydroxychloroquine and although more work is needed, this calls into question the role of these medications as preventive therapy.

Keywords: COVID19; Hydroxychloroquine; Pandemic; SARS-CoV-2.

Publication types

Case Reports