Risk factors for intra-abdominal abscess following laparoscopic appendectomy for acute appendicitis: a retrospective cohort study on 2076 patients

Updates Surg. 2020 Dec;72(4):1175-1180. doi: 10.1007/s13304-020-00749-y. Epub 2020 Apr 27.

Abstract

Background: Intra-abdominal abscesses (IAA) may develop after laparoscopic appendectomies (LA) for acute appendicitis. The identification of risk factors for postoperative IAA could lead to a decrease in the readmission rate and surgery redoes after LA for acute appendicitis.

Materials and methods: The present study retrospectively analyzed patients undergone LA for acute appendicitis during the period 2001-2017. Clinical, intraoperative, and postoperative outcomes were described. Comparison between groups was made via univariate and multivariate analyses.

Results: The charts of 2076 patients undergone LA were reviewed. Thirty-seven patients (1.8%) developed a postoperative IAA. Male gender (p < 0.05), ASA score ≥ 2 (p < 0.05), a gangrenous or perforated appendicitis (p < 0.0001), abscess or pelvic peritonitis (p < 0.0001), clipping the mesoappendix (p < 0.0001), appendix division by mechanical stapler (p < 0.05), prolonged antibiotic therapy (p < 0.05), and piperacillin/tazocin regimen (p < 0.0001) were significantly more frequent in the group of patients with IAA. In terms of multivariate analysis, only pelvic peritonitis (p = 0.010), perforated appendicitis (p = 0.0002), and clipping the mesoappendix (p = 0.0002) were independent predictive factors for postoperative IAA.

Conclusion: Patients with peritonitis or a perforated appendicitis, and those who had their mesoappendix clipped showed a higher likelihood of developing an IAA. At risk patients should be provided with careful follow-up for the early detection and management of this complication.

Keywords: Acute appendicitis; Appendicular stapling; Clipping mesoappendix; Laparoscopic appendectomy; Postoperative intra-abdominal abscess.

MeSH terms

  • Abdominal Abscess / epidemiology
  • Abdominal Abscess / etiology*
  • Acute Disease
  • Adolescent
  • Adult
  • Appendectomy / methods*
  • Appendicitis / surgery*
  • Child
  • Cohort Studies
  • Female
  • Humans
  • Laparoscopy / methods*
  • Male
  • Peritonitis
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology*
  • Retrospective Studies
  • Risk Factors
  • Surgical Instruments
  • Treatment Outcome
  • Young Adult