Antiviral, Cytotoxic and Antioxidant Effects of Tanacetum Vulgare L. Crude Extract In Vitro

Folia Med (Plovdiv). 2020 Mar 31;62(1):172-179. doi: 10.3897/folmed.62.e49370.

Abstract

Introduction: Due to the high prevalence of viral infections having no specific treatment and the constant emergence of resistant viral strains, searching for effective antiviral compounds is crucial. The present study explores in vitro the antiviral activity of ethanolic extract from aerial parts of.

Aim: The aim of the current study was to evaluate antiviral activity of ethanolic extract from herbaceous plant.

Materials and methods: The crude aqueous ethanolic extract from aerial parts of.

Results: The results show that the extract has the lowest toxicity on the MDBK cell line and similar cytotoxicity in Hep-2, whereas in the MDCK cells it has more than twice the highest toxicity. Testing the antiviral activity of.

Conclusion: The crude extract from aerial parts of the medicinal plant.

Keywords: CVB1; H3N2; HSV-1; Tanacetum vulgare L.; antioxidant activity.

MeSH terms

  • Animals
  • Antioxidants
  • Cell Survival / drug effects
  • Dogs
  • Enterovirus B, Human / drug effects*
  • Epithelial Cells / drug effects
  • Ethanol
  • Herpesvirus 1, Human / drug effects*
  • Humans
  • In Vitro Techniques
  • Influenza A Virus, H3N2 Subtype / drug effects*
  • Influenza A virus / drug effects
  • Madin Darby Canine Kidney Cells
  • Microbial Viability / drug effects*
  • Plant Components, Aerial
  • Plant Extracts / pharmacology*
  • Solvents
  • Tanacetum*
  • Thiobarbituric Acid Reactive Substances / metabolism
  • Virion / drug effects
  • Virus Replication / drug effects

Substances

  • Antioxidants
  • Plant Extracts
  • Solvents
  • Thiobarbituric Acid Reactive Substances
  • Ethanol