Merging Magnetoencephalography into Epilepsy Presurgical Work-up Under the Framework of Multimodal Integration

Joon Yul Choi; Zhong Irene Wang

doi:10.1016/j.nic.2020.01.005

Merging Magnetoencephalography into Epilepsy Presurgical Work-up Under the Framework of Multimodal Integration

Neuroimaging Clin N Am. 2020 May;30(2):249-259. doi: 10.1016/j.nic.2020.01.005. Epub 2020 Apr 2.

Authors

Joon Yul Choi¹, Zhong Irene Wang²

Affiliations

¹ Epilepsy Center, Neurological Institute, Cleveland Clinic, Desk S51, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
² Epilepsy Center, Neurological Institute, Cleveland Clinic, Desk S51, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: wangi2@ccf.org.

PMID: 32336411
DOI: 10.1016/j.nic.2020.01.005

Abstract

Multimodal image integration is the procedure that puts together imaging data from multiple sources into the same space by a computerized registration process. This procedure is relevant to patients with difficult-to-localize epilepsy undergoing presurgical evaluation, who typically have many tests performed, including MR imaging, PET, ictal single-photon emission computed tomography, magnetoencephalography (MEG), and intracranial electroencephalogram (EEG). This article describes the methodology of such integration, focusing on integration of MEG. Also discussed is the clinical value of integration of MEG, in terms of planning of intracranial EEG implantation, interpretation of intracranial EEG data, planning of final resection, and addressing surgical failures.

Keywords: Epilepsy; ICEEG; MEG; Multimodal; Presurgical evaluation; SEEG.

Publication types

Review

MeSH terms

Electroencephalography
Epilepsy / diagnostic imaging*
Epilepsy / physiopathology
Epilepsy / surgery
Humans
Magnetic Resonance Imaging
Magnetoencephalography*
Multimodal Imaging